Signalling mechanisms for limbal stem cells and corneal epithelial maintenance
If you have any partnering opportunities for Regener8 members, please contact us.
NESCI would be interested in funding / studentship opportunities for the following proposal.
NESCI are interested in industrial partners who may like to collaborate in one of these fields (for a CASE studentship or other awards), or in anyone who is interested in these areas of research (including other academic groups). For further details, please contact Helen Clamp from NESCI.
Project: Signalling mechanisms for limbal stem cells and corneal epithelial maintenance
Lead: Dr Sajjad Ahmad
The cornea is the clear front of the eye and its clarity is vital for normal visual functioning. The cornea is covered by an epithelium which is renewed by stem cells located at the periphery of the cornea, in a region known as the limbus. Little is known about the signalling mechanisms maintaining limbal stem cells. Gene microarray studies will be used to identify and investigate such mechanisms. By understanding these mechanisms, new treatments can be developed for patients blinded by a deficiency of limbal stem cells.
