The constuction of an in vitro corneal bio-construct
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NESCI would be interested in funding / studentship opportunities for the following proposal.
NESCI are interested in industrial partners who may like to collaborate in one of these fields (for a CASE studentship or other awards), or in anyone who is interested in these areas of research (including other academic groups). For further detaiols, please contact Helen Clamp from NESCI.
Project: The constuction of an in vitro corneal bio-construct
Lead: Dr Sajjad Ahmad
The cornea is the clear front of the eye. There are approximately 6 million people blinded by corneal disease worldwide. The conventional management of corneal scarring is by the transplantation of cadaveric cornea. There is however a shortage of donor corneas. In this project, the construction of an in vitro corneal bio-construct will be investigated using stem cells and tissue engineering techniques. The cornea is composed of three main layers: an epithelium, a stroma and an endothelium. Construction of these three layers separately in the first instance will be investigated, followed by a combination of all three layers. This will be used to develop a corneal bio-construct which can be used for corneal tranplantation in the future.
